stimulating cAMP accumulation in Chinese hamster ovary cells expressing the human β3-AR
GSK650394 inhibits SGK1-mediated epithelial transport with an IC50 of 0
whereas the erythroid markers CD235a and CD71 are downregulated by this treatment
Quaternary amine compounds and antibody-drug conjugates thereof
InChi: InChI=1S/C23H18ClF2N3O3S/c1-2-9-33(31
MK-0429 ide) stimulating cAMP accumulation in ChineseMK 0429 (L 000845704) is an orally active, potent, selective and nonpeptide pan integrin antagonist with IC50 values of 1. 6 nM, 2. 8 nM, 0. 1 nM, 0. 7 nM, 0. 5 nM and 12. 2 nM for v1, v3, v5, v6, v8 and 51, respectively. Product information CAS Number: 227963 15 7 Molecular Weight: 439. 51 Formula: C23H29N5O4 Chemical Name: (3S) 3 (6 methoxypyridin 3 yl) 3 {2 oxo 3 [3 (5,6,7,8 tetrahydro 1,8 naphthyridin 2 yl)propyl]imidazolidin 1 yl}propanoic acid